Environment, diet, emotion, conditions of working and resting are the four causes that will lead to the disorder of Yin and Yang, Qi and blood and also the function of viscera in human body , at the same time , they will produce three kinds of pathological processes as follows: three fire exuberance damaging yin, three Qi deficiency zhi yang and three Yin deficiency will be in failure. Symptoms above will form 3 kinds of Disease: less water in flesh which will become thin, less water in blood which become blood thick, and less water in marrow which will be in failure. Three lesions will produce two types of pathology: blood thick of yin deficiency blood heat and blood thick of yang deficiency blood cold , these two pathological products are the main reasons that cause diabetes into the condition of less hot water which become thin, cold flesh thick water which become Swollen fat. Hot blood less water causes XIAOKE, cold blood water coagulation becomes exhausted. Less medullary more water will cause frequency of urination. Less medullary less water will be in failure. Two types of pathology mentioned above are the main reasons of the 6 specific symptoms.

Flesh heat dates back to liver and heart, blood cold dates back to spleen and lung failure of marrow dates back to heart and kidney. Stomach fire, liver fire and heart fire generate blood thick which belongs to the type of blood heat. Although the index of blood sugar and urine sugar is high , we call it SANDUOYISHAO in TCM , there is still healthy Qi in human body ; deficiency of lung Qi , spleen Qi and kidney Qi will generate blood thick which belongs to the type of blood Solidification, we call it SANDUOYISHAO also , the index of blood sugar and urine sugar is not abnormal obviously in such kind of situation, but it is getting to the middle period of healthy Qi deficiency, the stage of failure in heart yin , spleen yin and kidney yin can be called the late period of deficiency of dual Yin and Yang.